2008-2015年广东省深圳市宝安区感染性腹泻致病菌监测结果分析

The surveillance results of the pathogenic bacteria of infectious diarrhea in Bao' an District in Shenzhen City of Guangdong Province from 2008 to 2015

目的了解深圳市宝安区感染性腹泻致病菌感染现况。方法选取深圳市宝安区腹泻哨点监测医院门诊未使用过抗生素病例的粪便、肛拭子或呕吐物标本,进行9种致病菌的分离、培养和鉴定,对阳性菌株进行血清型别检测,利用SAS统计软件分析病原菌的流行病学分布、特征。结果深圳市宝安区腹泻哨点监测中感染性腹泻致病菌感染率为19.32%,检测出副溶血弧菌、肠产毒性大肠埃希菌(ETEC)在不同年龄组差异有统计学意义(P<0.05),以副溶血弧菌感染为主。沙门菌、副溶血弧菌、肠侵袭性大肠埃希菌(EIEC)、ETEC等感染有时间分布差异,沙门菌和副溶血弧菌感染高峰期在夏、秋季;户籍、常住与流动人口在沙门菌、副溶血弧菌、肠致病性大肠埃希菌(EPEC)、EIEC、ETEC、志贺菌感染构成比中差异有统计学意义(P<0.01);男女性别比在沙门菌、副溶血弧菌、ETEC及志贺菌的分布上差异有统计学意义(P<0.05)。结论深圳市宝安区要重点加强辖区内副溶血弧菌感染的防治,6~10月要加强沙门菌、副溶血弧菌等肠道致病菌的监测与防治,加强暂住人群肠道传染病防治知识宣教。

Objective To study the pathogenic bacteria of infectious diarrhea in Bao＇ an District in Shenzhen City. Methods Stool samples, rectal swabs or vomit samples of no use antibiotics patients that visited sentinel hospital in Bao＇ an District were selected to isolate and culture pathogenic bacteria. The serotypes of the positive strains were detected, and SAS statistics software was used to analyze epidemiological distribution and characteristics. Results The infection rate of infectious diarrhea was 19. 32% in sentinel surveillance of Baohn District in Shenzhen, parahaemolyticus and enterotoxigenic Escherichia coli （ ETEC ） in and there were significant differences in the detection of Vibrio different age groups （ P 〈 0. 05 ） , and Vibrio parahaemolyticus was the main infection. Salmonella, Vibrio parahaemolyticus, EIEC and ETEC were different in the time of infection. Salmonella and Vibrio parahaemolyticus infection peaked in summer and autumn. Household registration, resident and floating population in Salmonella （ P 〈 0.01 ）. The sex ratio of male and female was higher than that of Salmonella, Vibrio parahaemolyticus, Salmonel- la typhimurium, Salmonella typhimurium, Salmonella parahaemolyticus, Ecoli, EECEC, ETEC and Shigella. There were sig- nificant differences Vibrio parahaemolyticus, ETEC and Shigella were significantly different （ P 〈 0. 05 ）. Conclusion We must focus on strengthening the prevention and treatment of Vibrio parahaemolyticus infection, strengthening the surveillance and pre- vention of Salmonella and Vibrio parahaemolyticus from June to October especially, strengthening the health education and pro- motion of intestinal infectious disease in floating population.