结肠型克罗恩病手术治疗原则

Surgical strategy for colonic Crohn's disease

克罗恩病(Crohn’s disease,CD)临床表现复杂,目前尚无根治性的治疗方案。CD可发生于消化道任何部位,随着病情进展,可出现狭窄、梗阻、恶变、穿孔、瘘管等并发症,须及时外科干预。结肠型CD具有特有的临床表现及疾病转归,使其处理策略有别于其他部位的病变。正确把握手术时机并权衡手术利弊,选择合适手术时机及手术方式,在多学科综合治疗协作组模式下制定适合病人的个体化临床决策与方案,可使病人获益更多。

Clinical manifestations of Crohn’s disease（CD） varies from person to person. No curative treatment is available yet. CD occurs at any site of the GI tract. As the disease evolves, complications such as stricture, obstruction, malignant transformation, penetration and fistulas eventually occur, and surgery is demanded accordingly. With specific clinical features and prognosis of colonic CD, the therapeutic strategy is different from CD of other sites. Patients benefit more when pros and cons of the surgery are carefully weighed and when the surgery is performed in the appropriate approach at the right moment along with personalized therapy with multidisciplinary cooperation.