酪酸梭菌散联合四磨汤口服液治疗新生儿肠痉挛的疗效观察

Effect of Clostridium butyricum combined with Si Mo decoction in treating neonatal intestinal spasm

目的观察酪酸梭菌散联合四磨汤口服液在新生儿肠痉挛治疗中的效果。方法选取产科母婴同室中诊断为肠痉挛的162例新生儿作为研究对象,随机分为三组,治疗组54例,对照A组57例和对照B组51例。全部病例均进行常规护理,同时对照A组给予酪酸梭菌散口服,对照B组给予四磨汤口服液口服,治疗组同时给予酪酸梭菌散和四磨汤口服液口服,观察5d后三组的治疗效果。结果治疗组的总有效率为92.59%,对照A组的总有效率为77.19%,对照B组的总有效率为70.59%,治疗组总有效率高于两组对照组,差异有统计学意义(P<0.05)。结论酪酸梭菌散联合四磨汤口服液在新生儿肠痉挛治疗中效果显著,值得临床应用。

Objective To observe the efficacy of Clostridium butyricum combined with Si Mo decoction in treating neonatal intestinal spasm.Methods 162 newborns diagnosed as neonatal intestinal spasm were included as the subjects,who were randomly divided into the treatment group（54cases）,control group A（57cases）or control group B（51cases）.All the cases were given routine nursing care,meanwhile the treatment group was given Clostridium butyricum and Si Mo decoction orally,the control group A was given Clostridium butyricum alone orally,and the control group B was given Si Mo decoction alone orally.The clinical effects in three groups after treatment for 5days were observed.Results The total efficiency rate was 92.59%in the treatment group,significantly higher than that in the control group A（77.19%）and in the control group B（70.59%）（P〈0.05）.Conclusion Clostridium butyricum combined with Si Mo decoction has remarkable efficacy in the treatment of neonatal intestinal spasm.