健益方治疗儿童哮喘缓解期肺脾气虚证疗效观察

Clinical observation on Jianyi decoction in the treatment of asthmatic children in remission stage with syndrome of deficiency of lung and spleen qi

目的评价健益方治疗儿童哮喘缓解期肺脾气虚证的临床疗效。方法 2015年2月至2016年4月上海市东方医院和上海市中医医院儿科收治门诊及住院的哮喘缓解期患儿80例,随机分为对照组和观察组各40例。对照组按GINA方案给予普米克令舒(布地奈德)雾化吸入;观察组用健益方加减治疗;疗程均为6个月。观察并比较两组治疗前后主要症状体征积分变化及临床疗效。结果观察组在控制哮喘发作总有效率为87.5%(35/40),与对照组92.5%(37/40)疗效相当,差异无统计学意义(P>0.05);观察组在治疗前后各项主证积分值均有明显改善,明显优于对照组,差异有统计学意义(P<0.05)。结论健益方治疗哮喘缓解期肺脾气虚证患儿疗效肯定,值得临床应用推广。

Objective To evaluate the clinical efficacy of Jianyi decoction（JYD）in the treatment of asthmatic children with syndrome of deficiency of lung and spleen qi.Methods Totally 80 children with asthma in remission stage from February 2015 to April 2016 were divided into control group and observation group.The control group（40cases）were given Pulmicort neblizing treatment.The observation group（40cases）were treated with Chinese medicine Jianyi decoction.The score change of major symptoms and signs as well as the clinical effect between the two groups were observed after 6-month treatment.Results The total effective rate was 87.5%in observation group,which had no statistical difference from control group（P〉0.05）;the observation group was superior to control group in improvement of main symptoms and signs with statistical significant difference（P〈0.05）.Conclusion The treatment of administration of JYD for asthmatic children with syndrome of deficiency of lung and spleen qi is effective.It is worthy of clinically spreading.