缩宫素联合米索前列醇治疗子宫收缩乏力致产后出血的临床疗效观察

Clinical Effect of Oxytocin Combined Misoprostol in the Treatment of Postpartum Hemorrhage Caused by Uterine Atony

目的:观察缩宫素联合米索前列醇用于子宫收缩乏力导致的产后出血的治疗效果。方法:将84例由于子宫收缩乏力导致产后出血的患者随机分为试验组、对照组各42例,其中试验组治疗方案为缩宫素联合米索前列醇,对照组为单纯缩宫素,观察比较两组出血量、不良反应发生情况、宫缩恢复时间、子宫切除率。结果:试验组各时段出血量及宫缩恢复时间均显著优于对照组(P<0.05);试验组子宫切除率2.38%,显著低于对照组14.29%(P<0.05);试验组不良反应发生率11.90%,与对照组7.14%相比无显著差异(P>0.05)。结论:米索前列醇联合缩宫素用于治疗子宫收缩乏力导致的产后出血效果较单纯缩宫素治疗更为理想,且并未明显增加不良反应发生率,安全可靠,值得在临床上推广。

Objective：To observe the therapeutic effect of oxytocin combined with misoprostol in the treatment of postpartum hemorrhage caused by uterine atony.Methods：84cases patients with postpartum hemorrhage caused by uterine atony were randomly divided into experimental group and control group,with42 cases in each group.The experimental group was given oxytocin combined misoprostol treatment,and the control group was only given oxytocin treatment,then the bleeding volume,incidence of adverse reactions,recovery time of uterine contraction,and the resection rate of uterus of two groups were observed and compared.Results：The bleeding volume in time frame and recovery time of uterine contraction of experimental group were significantly better than those of control group（P〈0.05）;The resection rate of uterus of experimental group（2.38%）was significantly lower than that of control group（14.29%）（P〈0.05）;There was no significant difference in the incidence of adverse reactions between the two groups（11.90%in experimental group and 7.14%in control group）（P〉0.05）.Conclusion：Misoprostol combined oxytocin in the treatment of uterine atony caused by postpartum hemorrhage has more ideal treatment effect,with no significant increase of the incidence of adverse reactions,which is safe,reliable,and worthy of clinical promotion.