复方三七散外敷防治甘露醇所致静脉炎效果观察

Observation on Effects of External Application of Compound SanQi Powder in Preventing and Treating Phlebitis Caused by Mannitol

目的:观察复方三七散防治静脉留置针输注甘露醇所致静脉炎的效果。方法:将脑出血、脑梗死或脑炎而使用甘露醇的患者136例随机分为硫酸镁治疗组和复方三七散治疗组。2组在使用静脉留置针输注20%甘露醇治疗时,硫酸镁治疗组穿刺静脉局部给予50%硫酸镁溶液浸湿纱布外敷;复方三七散治疗组给予复方三七散药粉和70%酒精混合的药糊外敷。对2组静脉留置针留置时间进行观察。对已发生静脉炎患者按静脉炎的程度分为Ⅰ级患者和Ⅱ级患者。每级患者又分为硫酸镁治疗组和复方三七散治疗组。每组给予相应的药物进行外敷治疗,以5天(120小时)为期,观察2组效果。结果:2组患者静脉留置针留置时间比较显示酸镁治疗组的留置时间(71.0±18.8)h少于复方三七散治疗组留置时间(98.0±14.3)h(P<0.05)。已发生静脉炎的Ⅰ、Ⅱ级患者的治疗效果显示复方三七散治疗组优于硫酸镁治疗组(P<0.05)。结论:复方三七散外敷具有防治静脉留置针输注甘露醇时所致的静脉炎的作用,且效果优于硫酸镁湿敷。

Objective： To observe the effects of compound SanQi powder in preventing and treating phlebitis caused by injecting Mannitol with venous indwelling needle. Methods： All 136 patients with cerebral hemorrhage, cerebral infarction, encephalitis, and who were given mannitol, were randomly divided into the treatment group of magnesium and the treatment group of compound SanQi powder. Both groups were given 20% mannitol by venous indwelling needle, the treatment group ofmagnesiurn were given local venous puncture of gauze soaked with 50% magnesium solution for external application; the treatment group of compound SanQi powder were given poultice of compound SanQi powder mixed with 70% alcohol for external application. The indwelling time of venous indwelling needle were observed in two groups. Patients with phlebitis were divided into class I and class II according to the degree of phlebitis. Patients of each class were divided into the treatment group of magnesium and the treat- ment group of compound SanQi powder. Each group accepted corresponding herbs for external application for five days （120 hours）, the effects of two groups were observed. Results： The indwelling time of venous indwelling needle of patients in two groups were compared, the indwelling time of the treatment group of magnesium （71.0± 18.8）h was less than that of the treatment group of compound SanQi powder （98.0±14.3） h（P〈0.05）. The effects for the patients with phlebitis in classes I and II showed that the treatment group of compound SonQi powder was better than the treatment group of magnesium（P〈0.05）. Conclusion： Compound SanQi powder for external application can prevent and treat phlebitis by mannitol with venous indwelling needle, and the effects are better than magnesium wet compress.