摘要
Fluoride is soluble in water and accumulates in bone when absorbed by organism. Fluoride influences bone turnover by regulating certain factors, such as runt-related transcription factor 2 （Runx2） and receptor activator for nuclear factor-KB ligand （RANKL）, which act as markers of osteoblasts and osteoclasts.
Fluoride is soluble in water and accumulates in bone when absorbed by organism. Fluoride influences bone turnover by regulating certain factors, such as runt-related transcription factor 2 （Runx2） and receptor activator for nuclear factor-KB ligand （RANKL）, which act as markers of osteoblasts and osteoclasts.
