H型高血压与缺血性脑卒中预后分析

Correlation Analysis on H-type hypertension and prognosis for cerebral ischemic stroke

目的:探讨高血压患者的血浆同型半胱氨酸(Hcy)水平与缺血性脑卒中再发风险的相关性。方法:对260例缺血性脑卒中患者进行随访4年,将所有对象分为仅有高Hcy水平、仅有高血压、无高Hcy水平合并有高血压、高Hcy水平合并有高血压4种情况,多种统计方法探讨高血压伴有血浆高同型半胱氨酸患者与缺血性脑卒中再发风险的关系。结果:血浆高同型半胱氨酸(P<0.0005)与高血压(P<0.0001)分别是缺血性脑卒中复发的危险因素,在考虑高血压因素与血浆高同型半胱氨酸的协同作用时,高血压伴高同型半胱氨酸水平对缺血性脑卒中的复发有显著影响(P<0.05)。结论:H型高血压患者是缺血性脑卒中复发和再发的重要危险因素。

Objective：To explore the relationship between plasma homocysteine（Hcy） level of patients with hypertension and recurrence risk of cerebral ischemic stroke.Methods：260 patients with cerebral ischemie stroke, having been seen for follow-up visits for 4 years, were divided into 4 cases--high Hey,hypertension, no high Hey or hypertension,hypertension complicated with high Hcy; several statistic methods were applied to analyze the relationship between the ease of hypertension complicated with high plasma homocysteine and recurrence risk of cerebral ischemic stroke.Results：High plasma homocysteine（P〈 0.0005） and hypertension（P〈 0.0001） were respectively the risk factors for cerebral ischemic stroke; meanwhile in considering the synergistic action of hypertension and high plasma homocysteine, the case level of hypertension complicated with high plasma homocysteine had a significant effect on recurrence risk of cerebral ischemic stroke（P〈 0.05）.Conclusioin：Elevated levels of hypertension complicated with high plasma homocysteine（H-type hypertension） are important risk factors for the palindromia and recurrence of cerebral ischemic stroke.