两种量表在血管性认知功能障碍评估中的应用研究

Application of the two scales in acute cerebral infarction vescular cognitinve impairment

目的:比较简易精神状态量表(MMSE)和中文版蒙特利尔认知评估量表(MoCA)在脑梗死后血管性认知功能障碍(VCI)中的应用。方法:收集急性脑梗塞后血管性认知功能障碍患者75例(病例组)及健康人群68例(对照组),分别应用MMSE及MoCA进行神经心理学测验,比较二者子项目得分在筛查急性脑梗死后血管性认知功能障碍中的特点。结果:除定向力和抽象能力外,病例组与对照组在MoCA的其他子项目的比较均有统计学差异(P<0.05);病例组和对照组在MMSE的子项目中地点定向力、计算与注意、延迟回忆、复述、表达、绘图6项比较有统计学差异(P<0.05),其余各项差异均无统计学意义(P>0.05)。结论:MoCA较MMSE更能体现VCI的临床心理学特点。

Objective： To investigate the application of MMSE and MoCA in acute cerebral infarction cognitive impairment. Methods： Collecting 143 cases, 75 cases in patients group and 68 cases in control group. Neuropsycho-logical tests were performed on 75 cases of cerebral infarction victims and 68 healthy patients assessed respectively by Mini-mental state examination （MMSE） and Montreal cognitive assessment （MoCA） ,compared the scores of sub-tests between MMSE and MoCA in screening characteristic of vascular cognitive impairment after acute cerebral in-farction. Results： There was significant statistical meaning in comparation between patients group and control group （P〈0 . 05） ,excepted orientation and Abstraction. There was significant statistical meaning in place orientation,calcu-lation and attention delay memory, restatement, expression, drawing（P〈0. 05）;There was no significant statistical meaning in rest of subtests （P〉0. 05）. Conclusion： It＇s better that MoCA than MMSE reflect the clinical psychol-ogy characteristics of VCI.