CRP、PCT检验在高脂血症性急性胰腺炎诊断中的应用价值及病程的关系研究

Application Value of CRP and PCT in the Diagnosis of Hyperlipidemic Acute Pancreatitis and Its Relationship with Disease

目的:探究高脂血症性急性胰腺炎(AP)的临床特点以及C反应蛋白(CRP)及降钙素原(PCT)在高脂血症性胰腺炎严重程度评价中的作用,探讨其对高脂血症性急性胰腺炎预后评估的临床价值。方法:选取我院2014年9月~2015年9月收治的128例急性胰腺炎患者,以64例高脂血症性胰腺炎患者为观察组,64例胆源性胰腺炎患者为对照组。比较两组患者的临床特征。结果:急性高脂血症性胰腺炎与胆源性胰腺炎相比糖尿病发生率、脂肪肝发生率和血脂水平较高,肝功能受损程度和血清淀粉酶水平较低,差异有统计学意义(P<0.05)。结论:CRP联合高血脂可作为高脂血症性急性胰腺炎严重程度的评价指标。CRP及PCT对高脂血症性急性胰腺炎预后评估具有经济、方便、可行、可较早诊断等临床价值。

Objective：To explore the clinical features of hyperlipidemic acute pancreatitis as well as C-reactive protein（CRP） and procalcitonin（PCT） evaluation of the severity of pancreatitis in hyperlipidemic acute pancreatitis.To evaluate the clinical value of hyperlipidemic acute pancreatitis prognosis.Methods：128 patients with acute pancreatitis from Sept 2014 to Sept 2015 who was treated in the author＇s hospital were selected,and 64 cases with hyperlipidemic acute pancreatitis（HLAP） were selected in the observation group,while 64 cases with biliary acute pancreatitis（BAP） in the control group.The clinical features of the two groups were compared.Ranson and CT scores were compared before and after,as well as two groups of serum lipids and CRP levels.Results：The hyperlipidemic acute pancreatitis（HLAP） had a higher incidence of diabetes,fatty liver and lipid levels compared to biliary acute pancreatitis（BAP）,while a lower incidence of impaired liver function and serum amylase levels,differences was statistically significant {P〈0.05）.Conclusion：CRP combined with high cholesterol can be used as the evaluation index to hyperlipidemic acute pancreatitis severity.