振幅整合脑电图在窒息早产儿脑损伤及脑发育监测中的应用

Application of Amplitude Integration of Electroencephalogram(eeg) in Premature Infant Brain Injury and Brain Development Monitoring

目的:探析振幅整合脑电图在窒息早产儿脑损伤及脑功能监测应用效果。方法:选取2015年12月~2016年2月我院新生儿科/NICU72例窒息早产儿和72例单纯早产无窒息史的患儿作为研究对象纳入脑损伤组,另选取足月新生儿科高危新生儿72例作为对照组,两组研究对象都连接振幅整合脑电图进行监测,对比两组脑电图显示结果。结果:对照组脑电图电压呈连续性的新生儿占95.83%(69/72),睡眠呈周期性的新生儿占比97.22%(70/72);均分别显著高于脑损伤组的29.17%(21/72),33.33%(24/72),差异均有统计学意义(均P<0.05)。对照组监测结果背景活动非正常者占比31.94%(13/72)显著低于脑损伤组的86.11%(62/72),差异具有统计学意义(均P<0.05)。结论:振幅整合脑电监测在窒息早产儿脑损伤的诊断中,能够早期、更敏感地发现病变,这更加利于临床做出诊断并给予治疗,提升患儿的生存率。

Objective：To analyze the amplitude integration of electroencephalogram（EEG） in premature infant brain injury and brain function monitoring application effect.Methods：Choose 2015 in December,2016 to February from neonatal units/NICU72 suffocation premature infants and 72 cases of simple with no history of asphyxia children as the research object into the brain injury group,the other selected full-term newborn pediatric high-risk neonates 72 cases as control group,both groups are connected amplitude integration eeg monitoring,compared two groups of electroencephalogram（eeg） showstheresult.Results：Electroencephalogram（EEG） of the control voltage is continuity of neonatal accounted for 95.83%（69/72）,and sleep a periodic newborn accounted for 97.22%（70/72）;Were significantly higher than that of brain injury group 29.17%（21/72）,33.33%（24/72）,the difference had statistical significance（P〈0.05）.The control monitoring results abnormal background activity accounted for 31.94%（13/72） was significantly less than 86.11%of the brain injury group（62/72）,statistically significant difference（P〈0.05）.Conclusion：Amplitude integration of eeg monitoring in the diagnosis of premature infant brain injury,to found early,more sensitive,pathological changes,it is more conducive to clinical diagnosis and give treatment,improve the patient＇s survival.