糖化血红蛋白和糖耐量试验在妊娠期糖尿病中的临床观察

Clinical Observation of Glycosylated Hemoglobin and Glucose Tolerance Test in Gestational Diabetes Mellitus

目的观察妊娠期糖尿病中糖化血红蛋白和糖耐量试验的临床应用情况。方法该院2016年1—10月门诊产检的80例妊娠期糖尿病孕妇(观察组)和90名正常孕妇(对照组)均进行空腹血糖、糖化血红蛋白和糖耐量试验检查,比较观察组不同期别孕妇治疗前糖化血红蛋白和糖耐量试验的检查情况。结果观察组空腹血糖、糖化血红蛋白水平高于对照组(P<0.05);观察组A1级和A2级孕妇糖化血红蛋白、空腹血糖、餐后1 h和2 h血糖的比较差异有统计学意义(P<0.05);高龄产妇组糖化血红蛋白水平高于低龄产妇组(P<0.05)。结论糖化血红蛋白和糖耐量试验对妊娠期糖尿病孕妇的诊治具有重要意义。

Objective To analyze the clinical significance of glycosylated hemoglobin and glucose tolerance test in pregnant women with gestational diabetes mellitus. Methods 40 cases of gestational diabetes pregnant women（observation group） and50 normal pregnant women（control group） from January to October 2016 in our hospital were given fasting blood glucose,glycosylated hemoglobin and glucose tolerance test.Comparison of the observation group before and after the treatment of different stages of the treatment of glycosylated hemoglobin and glucose tolerance test. Results The fasting blood glucose,GCT and glycosylated hemoglobin levels in the observation group were higher than those in the control group（P〈0.05）.In the observation group, the levels of glycosylated hemoglobin, fasting blood glucose, postprandial 1 h and 2 h blood glucose were statistically different between the A1 and A2 levels.and there was significant difference in the postprandial 3H blood glucose（P〈0.05）. Conclusion Glycosylated hemoglobin and glucose tolerance test is of great significance in the diagnosis and treatment of gestational diabetes mellitus.