甲状腺结节CT及病理分析

The CT and Pathological Analysis of Thyroid Nodules

目的:探讨64层螺旋CT对甲状腺结节的诊断价值及病理改变。材料与方法:甲状腺结节45例(良性25例,恶性20例)术前行CT扫描,同时术后行病理MVD及VEGF,并对各参数统计分析。结果:甲状腺良恶性结节形态、边界、囊变、包膜及肿大淋巴结有统计学差异(P<0.05),而结节数目、钙化无统计学意义(P>0.05);恶性组VEGF阳率及MVD计数高于良性组(P<0.05)。结论:CT客观显示甲状腺结节良恶性特征,MVD及VEGF反映病灶病理改变,对临床具有重要的指导意义。

Purpose： To investigate the diagnostic value of 64 slice spiral CT and the pathological changes in thyroid nodules. Materials and Methods： 45 cases （25 benign and 20 malignant） thyroid nodules were performed preoperative CT scan, the postoperative pathological MVD and VEGFwere performed at the same time, and then carried on the statistical analysis to each parameter. Results： The morphology, boundary, capsule, capsule, lymph nodes of benign and malignant thyroid nodules had significant difference （P 〈 0. 05 ）, but no significant the number and calcificationof nodules （ P 〉 0. 05 ）. The VEGF positive rate and MVD count of malignant group were higher than those of benign group （ P 〈 0. 05 ）. Conclusion： CT could objectively display the benign and malignant features of thyroid nodules, and MVD and VEGF reflect the pathological changes of the lesions, which had significant guiding for clinical.