207例男男性行为人群HIV/AIDS患者首次CD4^+T淋巴细胞检测分析

Analysis of the first CD4^+T lymphocyte test results in HIV/AIDS patients among men who have sex with men

目的了解湖州市新确证的男男性行为人群HIV/AIDS患者首次CD4^+T淋巴细胞水平及相关情况,为早期开展抗病毒治疗和现场干预提供依据。方法采用流式细胞仪对新确证的207例男男性行为人群HIV/AIDS患者进行首次CD4^+T淋巴细胞绝对值计数,统计分析其测定值。结果 207例患者中,CD4^+T淋巴细胞数最少为25个/μl,最多为1 006个/μl,平均(419.1±245.4)个/μl。其中≤200个/μl 38例,占18.4%(38/207);201个/μl^350个/μl 62例,占30.0%(62/207)。不同年龄、婚姻状况、文化程度男男性行为人群HIV/AIDS患者CD4^+T淋巴细胞结果比较,差异无统计学意义(P>0.05)。结论湖州市男男性行为人群HIV/AIDS患者首次CD4^+T淋巴细胞水平相对偏低,应加强对男男性行为人群艾滋病相关知识宣传,使更多的HIV感染者和发生高危行为的人尽早到相关医疗单位进行咨询检测,以便及早发现和提高早期抗病毒治疗的机会。

Objective To understand the CD4^＋T lymphocyte level and the related situation in new confirmed HIV/AIDS patients in men who have sex with men in Huzhou,so as to provide basis for antiviral therapy and early intervention.Methods 207 new confirmed HIV/AIDS patients accepted the first absolute value count of CD4^＋T lymphocyte by flow cytometry.And the measured value was conducted for statistical analysis.Results Among 207 cases of HIV/AIDS patients,CD4^＋T lymphocyte count was at least 25 cell/μl,the highest to 1 006 cell/μl,and average to 419.1 cell/μl ± 245.4 cell/μl.The ≤200 cell/μl accounted for 18.4%（38/207）,201 cell/μl-350 cell/μl accounted for 30.0%（62/207）.CD4^＋T lymphocyte result in HIV/AIDS men who have sex with men at different age,marital status,educational level,and there was no statistical significance on the difference（P〈0.05）.Conclusion The level of CD4^＋T lymphocyte in patients with HIV/AIDS men who have sex with men confirmed in our city is relatively low.We should strengthen the AIDS knowledge publicity in MSM,so that more people with HIV infection and high-risk behavior can receive consult and detection in relevant medical units as soon as possible,as well as early detection and early treatment of anti-virus.