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氯米芬与来曲唑对于多囊卵巢综合症合并不孕患者的促排卵作用的比较和分析 被引量:9

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摘要 目的:探讨氯米芬(CC)和来曲唑(LE)在多囊卵巢综合征(PCOS)导致不孕的患者中促排卵的作用。方法:选择2014年12月至2015年12月在我院妇产科治疗的多囊卵巢综合征导致不孕不育的患者100例,随机分为观察组(n=50)和对照组(n=50)。观察组和对照组分别在月经的第三天开始应用LE 5毫克和100毫克促排卵,连用5天。然后比较两组患者的卵泡数目以及子宫内膜厚度、内分泌指标、周期妊娠率等。结果:观察组和对照组分别有1 6例和7例妊娠,周期妊娠率分别为32%和14%。观察组明显高于对照组(P<0.01)。对照组和观察组的子宫内膜厚度分别为(9.4±0.2)毫米和(8.0±0.3)毫米(P<0.05)。促排卵后,对照组患者的血清雌激素、孕激素和黄体生成素水平较观察组高,而FSH和AMH水平低于观察组,差异有统计学意义(P<0.05)。结论:与对照组相比较,应用LE对于PCOS患者不孕不育患者进行促排卵治疗,对于子宫内膜的影响小,周期妊娠率高。
出处 《中国农村卫生》 2017年第3期43-43,45,共2页
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