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骨髓微环境调控骨髓增生异常综合征的作用及相关机制 被引量:1

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摘要 骨髓增生异常综合征(myelodysplastic syndrome,MDS)是一类起源于造血干细胞(hematopoietic stem cells,HSC)异常的克隆性疾病,其以无效造血导致外周血细胞减少、一系或多系髓系细胞发育异常及高风险向急性髓系白血病(acute myeloid leukemia,AML)转化为特点,是一种异质性、克隆性的HSC疾病。时至今日,MDS患者在治疗后仍有很高复发率,多数患者仍不可治愈。既往研究发现,
出处 《诊断学理论与实践》 2016年第6期550-555,共6页 Journal of Diagnostics Concepts & Practice
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