比较不同临床类型脑小血管病的血管性认知功能的损害差异

Comparison of Vascular Cognitive Impairment in Different Clinical Types of Cerebral Small Vessel Disease

目的对不同临床类型脑小血管病的血管性认知功能的损害差异性进行分析。方法将本院在2013年1月-2016年11月接诊的脑小血管病患者66例作为研究对象,均进行简易智能状态检查表检查（MMSE）、日常生活能力量表（ADL）、事件相关电位检查（P300）,比较不同类型脑小血管病患者的差异性。结果脑白质疏松合并腔隙性病灶患者在MMSE检测中的各项评分均低于其它患者,P300检测中,脑白质疏松并合并腔隙性病灶患者潜伏期明显延长,且波幅低于其它患者,P〈0.05,差异具备统计学意义。结论对于脑小血管病患者致病因素越多,血管性认知功能损害程度越严重。

Objective To analyze the difference of vascular cognitive function in different clinical types of cerebral small vessel disease damage. Methods In ourhospital,patients with cerebral small vessel disease in 66 cases were chose as the research object from January 2013 to November 2016. All of them were examined by mini mental state examination examination（MMSE）,activity of daily living scale（ ADL） check,event related potential（P300）,to compare the difference of different types of cerebral small vessel disease. Results After the comparison of leukoaraiosis and lacunar lesions in detection of MMSE scores were significantly lower than other patients. In P300 detection,leukoaraiosis and lacunar lesions in patients with prolonged incubation,and the amplitude was lower than other patients,P〈0.05,the difference has statistical significance. Conclusion For patients with cerebrovascular disease,the more pathogenic factors,the more serious the degree of vascular cognitive impairment.