安列克与欣母沛预防高危阴道分娩产后出血的效果对比研究

Comparison of the Effectiveness of Domestic and Imported Romethamine for the Prevention of Postpartum Hemorrhage

目的:对比安列克与欣母沛在预防高危阴道分娩产后出血中的疗效与安全性。方法:选取佛山市南海区第六人民医院2013年1月至2014年12月收治的145例有产后出血高危因素经阴道分娩产妇,随机分为观察组73例和对照组72例,观察组于胎儿娩出后臀部深肌注安列克250μg,对照组于胎儿娩出后臀部深肌注欣母250μg。比较两组产妇产后2 h出血量及产后出血率、不良反应发生率。结果:观察组与对照组产后2 h出血量分别为(224.8±34.3)m L、(212.6±41.0)m L,产后出血率分别为13.7%、11.1%,不良反应发生率分别为31.5%、33.3%,组间比较,差异均无统计学意义(P>0.05)。结论:安列克用于预防高危阴道分娩产后出血安全有效,与欣母沛效果相当,但价格较后者明显降低。

Objective To compare the domestic and imported romethamine in the treatment of postpartum hemorrhage. Methods 145 patients with high risk factors of maternal postpartum hemorrhage were treated by domestic or imported romethamine after delivery. Compared two groups of maternal postpartum hemorrhage 2 hours and postpartum hemorrhage rate,adverse reaction rate. Results There were no significant difference between the two groups in blood loss of 2h,the incidence of postpartum hemorrhage and adverse reaction.（P〉0.05）. Conelnsion The early use of domestic romethamine in the prevention of postpartum hemorrhage had the same effect comparecd with imported romethamine. But the fee of domestic romethamine is much lower,which is worthy of clinical application and popularization.