摘要
Three new phenolics（1–3） and twenty-eight known compounds（4–31） were isolated from an ethanolic extract of roots of Alangium chinense. Compound 11 exhibited antiviral activity against Coxsackie virus B3 with IC50 values of 16.89 mmol/L. Compounds 1, 10–17, 19–21, and 23 showed strong antioxidant activity against Fe^2＋-cysteine-induced rat liver microsomal lipid peroxidation, with IC50 values of 0.14–8.18 mmol/L.
Three new phenolics（1–3） and twenty-eight known compounds（4–31） were isolated from an ethanolic extract of roots of Alangium chinense. Compound 11 exhibited antiviral activity against Coxsackie virus B3 with IC50 values of 16.89 mmol/L. Compounds 1, 10–17, 19–21, and 23 showed strong antioxidant activity against Fe^2＋-cysteine-induced rat liver microsomal lipid peroxidation, with IC50 values of 0.14–8.18 mmol/L.
基金
supported by the National Science and Technology Project of China (No. 2009ZX09311-004)
the National Natural Science Foundation of China (No. 201072234)
