生物医学光学中NADH荧光检测技术的发展

Development of NADH Fluorescence Detection Technology in Biomedical Optics

NADH(还原型烟酰胺腺嘌呤二核苷酸)自1962年被发现至今已有五十多年了,在此期间,运用NADH及其相关技术进行医疗诊断与医学检测的方式不断发展,领域也不断扩大。从当前的研究成果来看,NADH因为其独有的性质在现代医学诊断与检测领域发挥了极大的作用,如实时、无损地监测脑部的活动;清晰、有效地识别不同种类的脑组织;抗细胞辐射损伤;抗辐射诱导的细胞凋亡;进行人体内的诸多平衡调节及人体生物钟调节等。本文将重点介绍在重要领域中的NADH研究和应用的突破。

As NADH（ reduced nicotinamide adenine dinucleotide） has been discovered over five decades since 1962,the using of NADH and its technique for medical diagnosis and medical testing methods emerge in an endless stream,the field is also expanding. From the current research results,NADH has played an important role in the field of modern medical diagnosis and detection because of its unique nature. Especially in the area of non-destructively monitoring brain activity in real-time,recognizing different kinds of brain tissue clearly and effectively,resisting cells radiation damage,resisting the apoptosis induced by radiation,regulating many balances in the human body and regulating human body biological clock. This paper will focus on the important areas of the breakthrough in NADH researches and adhibitions.