原发性肝脏淋巴瘤一例诊治讨论

Diagnosis and treatment of primary hepatic lymphoma： report of one case

原发性肝脏淋巴瘤（PHL）是一种极其罕见的结外淋巴瘤，目前尚无统一的诊治标准。其临床表现无特异性，容易与肝炎、肝脏原发和继发性肿瘤混淆，病理为诊断的金标准。通常认为该病的治疗与其他部位的结外淋巴瘤相似，应作为全身疾病来考虑，宜采用包括手术、化疗、放疗等在内的综合治疗模式。2014年2月山西医科大学附属肿瘤医院血液病诊疗中心收治1例33岁男性原发性肝脏弥漫大B细胞淋巴瘤患者，经8个周期化疗达完全缓解，至截稿时仍无病生存。

Primary hepatic lymphoma （PHL） is an extremely rare disease without any unified diagnostic criterion. The symptoms are usually nonspecific. Liver biopsy remains the most valuable tool for diagnosis of PHL. The predominant histology of PHL is diffuse large B-cell lymphoma. The therapeutic modalities are variable, including surgery, chemotherapy, radiotherapy, or combination of the various processes. This article described a 33-year-old man with diffuse large B-cell PHL who was treated at the Affiliated Cancer Hospital of Shanxi Medical University Blood Disease Diagnosis and Treatment Center in February 2014. The patient benefited from eight-cycle chemotherapy. At present, the patient is disease-free and undergoes regular follow-up.