期刊文献+

抗癌药物引起心脏毒性的生物标志物研究进展 被引量:4

下载PDF
导出
摘要 肿瘤治疗过程中,各类抗癌药物及放疗可以引起心脏毒性并发症,影响患者预后或导致死亡。蒽环类药物(包括阿霉素、表阿霉素、阿克拉霉素及柔红霉素等)广泛应用于实体肿瘤及血液系统(如白血病、乳腺癌和淋巴瘤等)的治疗,是引起心脏毒性损伤最常见化疗药物,临床数据显示其可引起进展性、不可逆性心脏毒性损害。心脏毒性可表现为心悸、心电图异常、左心室射血分数(left ventricular ejection fraction,LVEF)下降,
作者 罗霞 程黎明
出处 《内科急危重症杂志》 2017年第1期65-69,共5页 Journal of Critical Care In Internal Medicine
  • 相关文献

参考文献1

二级参考文献37

  • 1Cvetkovi'c RS,Scott LJ.Dexrazoxane:a review of its use for cardioprotection during anthracycline chemotherapy[J].Drugs,2005,65(7):1005-1024.
  • 2Barry E,Alvarez JA,Scully RE,et al.Anthracycline-induced cardiotoxicity:course,pathophysiology,prevention and management[J].Expert Opin Pharmacother,2007,8 (8):1039-1058.
  • 3Lipshultz SE,Lipsitz SR,Sallan SE,et al.Chronic progressive cardiac dysfunction years after doxorubicin therapy for childhood acute lymphoblastic leukemia[J].J Clin Oncol,2005,23(12):2629-2636.
  • 4Lipshultz SE,Colan SD,Gelber RD,et al.Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood[J].N EnglJ Med,1991,324(12):808-815.
  • 5Von Hoff DD,Layard MW,Basa P,et al.Risk factors for doxorubicin-induced congestive heart failure[J].Ann Intern Med,1979,91(5):710-717.
  • 6Swain SM,Whaley FS,Ewer MS,et al.Congestive heart failure in patients treated with doxorubicin:a retrospective analysis of three trials[J].Cancer,2003,97 (11):2869-2879.
  • 7Keefe DL.Anthracycline-induced cardiomyopathy[J].Semin Oncol,2001,28(4 Suppl 12):2-7.
  • 8Ganame J,Claus P,Uyttebroeck A,et al.Myocardial dysfunction late after low-dose anthracycline treatment in asymptomatic pediatric patients[J].J Am Soc Echocardiogr,2007,20 (12):1351-1358.
  • 9Robert J,Morvan VL,Smith D,et al.Predicting drug response and toxicity based on gene polymorphisms[J].Crit Rev Oncol Hematol,2005,54(3):171-196.
  • 10Lipshultz SE,Rifai N,Sallan SE,et al.Predictive value of cardiac troponin T in pediatric patients at risk for myocardial injury[J].Circulation,1997,96 (8):2641-2648.

共引文献226

同被引文献63

引证文献4

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部