短时受精-早期补救方法行ICSI与常规ICSI的临床对照研究

Clinical Control Study of Early Rescue ICSI After Short-period Fertilization Failure and Routine ICSI

目的对照研究短时受精-早期补救方法行ICSI的临床应用价值。方法分别统计并比较常规ICSI414个取卵周期和短时受精-早期补救ICSI 65个取卵周期的受精率、卵裂率、着床率、妊娠率、流产率和抱婴率。结果两组之间除了受精率差异有统计学显著性(p<0.01)外,其余观察指标均无差异(p>0.05)。虽然常规ICSI的受精率高于短时受精-早期补救ICSI,但是妊娠结局没有差别。结论短时受精-早期补救能有效的改善实验室观察到的短时受精障碍患者的临床结局。

Objective To compare the clinical outcome of early rescue ICSI after short-period fertilization failure and routine ICSI. Methods 414 cycles of routine ICSI and 65 cycles of early rescue ICSI were taken in the studies in XinJiang Jiayin hospital. The fertility rate, cleavage rate, ,nidation rate, pregnancy rate, abortion rate and live birth rate of the two groups were compared. Results The fertilization rate in routine ICSI group was statistically significant higher than that of the rescue ICSI group （p 〈 0.01）, and there was no statistically significant difference between the two groups in other indicator （p 〉 0.05）. Although the fertilization rate in routine ICSI group was higher, but the pregnancy outcomes were the same. Conclusion Early rescue ICSI after short-period fertilization can improve the clinical outcome of fertilization failure.