Science:科学家们发现了储存记忆的“房子”

科学家们第一次鉴定出了他们称之为可以储存记忆的“房子”。事实上，这是能够储存有关我们曾经以及现在的地理方位信息的神经元。随着这些特殊神经元的发现，我们有可能能够学习更多大脑记忆形成的机制。

The chained activation of neuronal assemblies is thought to support major cognitive processes, including memory. In the hippocampus, this is observed during population bursts often associated with sharp-wave ripples, in the form of an ordered reactivation of neurons. However, the organization and lifetime of these assemblies remain unknown. We used calcium imaging to map patterns of synchronous neuronal activation in the CA1 region of awake mice during runs on a treadmill. The patterns were composed of the recurring activation of anatomically intermingled, but functionally orthogonal, assemblies. These assemblies reactivated discrete temporal segments of neuronal sequences observed during runs and could be stable across consecutive days. A binding of these assemblies into longer chains revealed temporally ordered replay. These modules may represent the default building blocks for encoding or retrieving experience.