摘要
无氧条件下,环己烷作溶剂,以咪唑为酸性组分与芳香醛和芳香胺反应,通过多组分Mannich反应,"一锅法"合成7种新型咪唑基多芳胺类化合物,产率81%~88%。产物通过IR、1HNMR和元素分析确定。该方法具有操作简单、条件温和、产率高、选择性高等特点。
Under anaerobic conditions and cyclohexane as solvent,novel multi aromatic amine compounds were synthesized with imidazole,aromatic aldehydes and aromatic amines by three component one pot Mannich reaction.The yield reached 81%-88%.The products are confirmed by IR,-1HNMR and elemental analysis.This process has advantages of simple,mild conditions,high yield and high selectivity.
作者
耿师科
郝占忠
马学林
GENG Shi-ke HAO Zhan-zhong MA Xue-lin(Key Laboratory of Materials and Physical Chemistry, College of Chemistry, Baotou Normal College, Baotou 014030, China)
出处
《化学试剂》
CAS
北大核心
2017年第3期313-316,共4页
Chemical Reagents
基金
内蒙古自治区自然科学基金资助项目(2015MS0516
2016MS0521)
包头师范学院青年基金资助项目(BSYKJ2014-24)
