黑果菝葜根茎化学成分的研究

Chemical constituents from the rhizomas of Smilax glauco-china

目的对黑果菝葜Smilax glauco-china Warb根茎的化学成分进行研究。方法黑果菝葜乙醇提取物的正丁醇部位采用硅胶、Sephadex LH-20、半制备柱进行分离纯化,通过理化性质和波谱数据鉴定所得化合物的结构。结果从中分离得到10个化合物,分别鉴定为苯乙醇-β-D-龙胆二糖苷(1)、2-phenylethyl-O-β-D-xylopyranosyl-(1→6)-β-Dglucopyranoside(2)、phenylethyl D-rutinoside(3)、phenylethylβ-D-glcoside(4)、hydrangeifolinⅠ(5)、icariside D1(6)、calophymembranside B(7)、2-hydroxyphenol-1-O-β-D-glucopyranosyl-(6→1)-α-L-rhamnopyranoside(8)、β-谷甾醇(9)、胡萝卜苷(10)。结论所有化合物均为首次从该植物分离得到。

AIM To study the chemical constituents from the rhizomas of Smilax glauco-china Warb.METHODS The n-butanol fraction of ethanol extract of S.glauco-china was isolated and purified by silica,Sephadex LH-20 and semi-preparative column,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Ten compounds were isolated and identified as phenethanol-β-D-gentiobioside（1）,2-phenylethyl-O-β-D-xylopyranosyl-（1→6）-β-D-glucopyranoside（2）,phenylethyl D-rutinoside（3）,phenylethyl β-D-glucoside（4）,hydrangeifolinⅠ（5）,icariside D1（6）,calophymembranside B（7）,2-hydroxyphenol-1-O-β-D-glucopyranosyl-（6→1）-α-L-rhamnopyranoside（8）,β-sitosterol（9）,daucosterol（10）.CONCLUSION All the compounds are isolated from this plant for the first time.