北五味子化学成分的研究

Chemical constituents from Schisandra chinensis

目的研究北五味子Schisandra chinensis(Turcz.)Baill.的化学成分。方法北五味子95%乙醇提取物的乙酸乙酯部位采用硅胶和重结晶进行分离纯化,通过理化性质和波谱数据鉴定所得化合物的结构。结果从中分离得到10个化合物,分别鉴定为十二烷(1)、棕榈酸(2)、花生酸(3)、β-谷甾醇(4)、白桦脂酸(5)、五味子甲素(6)、五味子乙素(7)、五味子丙素(8)、戈米辛B(9)、五味子酯甲(10)。结论化合物1和5为首次从该植物中分离得到。

AIM To study the chemical constituents from Schisandra chinensis（Turcz.） Baill..METHODS The ethyl acetate fraction of 95% ethanol extract of S.chinensis was isolated and purified by silica column and recrystallization,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Ten compounds were isolated and identified as dodecane（1）,palmitic acid（2）,arachidic acid（3）,β-sitosterol（4）,betulinic acid（5）,deoxyschisandrin（6）,γ-schizandrin（7）,schizandrin C（8）,gomisin B（9）,schisantherin A（10）.CONCLUSION Compounds 1 and 5 are isolated from this plant for the first time.