外源性外泌体在细胞凋亡中的调控作用

Regulatory effect of exosome on cell apoptosis

外源性外泌体是一种纳米级的生物膜结构,由多种细胞分泌,广泛分布于唾液、血浆、乳汁等体液中,可直接或间接参与受体细胞及其微环境的生物信息转录。它可通过多种方式高效参与细胞凋亡的发生、发展,在病毒感染性疾病、肿瘤的发生和发展等生物进程中发挥着重要的作用。

Exosome, a nano-grade biological membrane structure, is secreted by multiple cells, widely distributing in saliva, plasma, milk and other body fluid. It can directly and indirectly take part in the biological information transcription between the receptor cells and their micro-environment. Recent studies have demonstrated that exosomes play pivotal roles in the occurrence and development of viral infectious diseases, tumors and other cell apoptosis related diseases via regulating the apoptosis in various ways.