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皮炎湿疹疾病进展与皮损微生物感染种类、数量及炎性因子的关联研究 被引量:26

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摘要 目的探讨皮炎湿疹疾病进展与其皮损微生物感染种类、数量及炎性因子的关联。方法于患者皮炎湿疹皮损部位皮肤、非皮损部位皮肤同时取材做微生物培养,对培养结果进行常规菌种鉴定和菌落计数,比较皮炎湿疹疾病进展组与无进展组患者的炎性因子检测结果。结果 125例皮炎湿疹患者的皮损处微生物培养阳性者共占66.40%,其中金黄色葡萄球菌检出率达到33.60%,较该组患者在非皮损部位细菌及真菌检出率明显升高(P<0.05);皮损进展继发感染的患者皮损部位金葡菌检出率76.67%显著高于临床皮损无进展患者及对照组(P<0.05);皮损进展继发感染患者血清中多种炎性介质的含量明显高于皮损无进展患者的指标(P<0.05)。结论皮炎湿疹疾病进展与其皮损部位金黄色葡萄球菌感染、金葡菌平均密度密切相关,相关炎性因子可能为皮炎湿疹早期诊治和预后评判提供参考。
出处 《河北医药》 CAS 2017年第6期865-867,共3页 Hebei Medical Journal
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