摘要
神经母细胞瘤（NB）属于神经内分泌性肿瘤，是儿童颅外最常见的恶性肿瘤，123/131I—MIBG全身显像诊断儿童NB及其复发转移灶的准确性高，是其分期和疗效评价的标准方法。131I-MIBG同时可用于难治性（高危及晚期）儿童NB及其复发、转移的治疗，与化疗、干细胞移植联合可缓解NB复发。笔者主要综述了123/131I-MIBG诊治儿童NB的临床应用及目前存在的问题。
As a type of neuroendocrine tumors, neuroblastoma （NB） is the most common extra-cra- nial solid tumor of childhood. 123/131 I-MIBG scintigraphy is a standard imaging modality in staging and evalu- ating therapeutic effect of pediatric NB with high accuracy. 131 I-MIBG treatment is effective for children with high-risk and relapsed/refractory NB. Combined with chemotherapy, stem cell transplantation, 131I-MIBG treatment shows efficacy in decreasing the relapse of pediatric NB. This review summarizes the application of MIBG scintigraphy and ,131I-MIBG treatment for pediatric NB.
出处
《中华核医学与分子影像杂志》
CAS
北大核心
2017年第3期173-176,共4页
Chinese Journal of Nuclear Medicine and Molecular Imaging
