重庆地区健康献血人群弓形虫抗体检测结果分析

Investigation and research on Toxoplasma gondii infection of volunteer blood donors in Chongqing,China

目的了解重庆地区健康献血人群弓形虫(TOX)感染现状。方法随机采集重庆市血液中心2015年3-8月半年间该地区的健康献血人群血清样本1001(人)份,采用ELISA法检测单份血清标本的TOX抗体,对比分析不同性别、年龄、职业及受教育程度献血者TOX阳性率。结果本组重庆健康献血人群TOX抗体阳性率8.49%(85/1 001)。其中检出TOX-IgG抗体阳性78例,阳性率7.80%(78/1 001);TOX-IgM抗体阳性7例,阳性率为0.7%(7/1001)。不同职业以及受教育程度间的献血人群中TOX阳性率有统计学差异(p<0.05)。结论重庆地区健康献血人群中存在一定的TOX感染率;应加强对献血者弓形虫感染的监测,对免疫缺陷等特殊受血者宜开展相应项目的血液筛查,以降低弓形虫感染可能引起的输血风险。

Objective To investigate Toxoplasma gondii（ TOX） infection in volunteer blood donors from Chongqing.Methods The IgG and IgM antibodies of toxoplasma in serum specimen were detected using ELISA kit. The serum of 1 001 healthy donors from March to August 2015 were detected in Chongqing Blood Center. Results 1 001 blood donors were screened for TOX antibody,of which 85 were tested positive,at a rate of 8. 49%（85 /1 001）. The positive rate of Tox-IgG was 7. 8%（78 /1 001）; the positive rate of Tox-IgM was 0. 7%（7 /1 001）. The differences of positive rates between profession and education were statistically and significantly different（ P〈0. 05）. Conclusion Because some positive results were found in healthy blood donors from Chongqing,the test of toxoplasmosis in the donors should be strengthened,in order to improve blood safety.