激光治疗早期喉癌术后对声带不同功能特征影响的网状Meta分析

The impact of laser treatment for postoperative different vocal functions in early laryngeal cancer:network Meta-analysis

目的:评价早期喉癌激光术后对声带不同功能特征的影响。方法:通过计算机网页检索医学相关的主要数据库:PubMed、Web of Science和Embase数据库,由2位工作人员同时对搜索的相文献进行阅读和筛选,从筛选的文献中提取与研究目的相关的数据。对提取的数据用Stata 14.0软件进行网状Meta分析,获取早期喉癌激光术后对声带不同声音特性的影响。结果:通过文献检索和筛选结果共纳入符合要求的文献9篇,统计学分析结果表明,激光手术治疗早期喉癌能够显著降低声嘶评估量表和嗓音障碍指数评估总分。结论:激光治疗早期喉癌术后,可以降低声嘶评估量表和嗓音障碍指数评估总分,提高术后声带总体功能,改善患者术后的生活质量,但喉癌术后早期声带在功能和生理方面没有明显的改善。

Objective：To evaluate the impact of postoperative vocal different functional characteristics with laser treatment for early laryngeal cancer.Method：Computer searching the major medical-related databases：PubMed,Web of Science and Embase,searching and screening by two staff members at the same time to read the relevant literatures,extraction of data and research related to the purpose from the selected literature.Using Stata14.0software analysis the extracted data with Bayesian network Meta-analysis,get the laser surgery of early laryngeal cancer effects of different voice characteristics of vocal cord.Result：A total of nine articles was included finally according through the necessary conditions,statistical analysis results showed that early laryngeal laser surgery can significantly reduce GRABS and VHI assessment score.Conclusion：Laser treatment of early laryngeal cancer could reduce VHI and the GRABS assessment score postoperatively,improve overall postoperative vocal cord function and the quality of life of patients after surgery,but not in the early post-operative function and physiology in vocal function.