摘要
单病例随机对照试验设计提供了一种方法来对单个患者的治疗进行最佳决策,本文简要介绍单病例随机对照设计的适用对象、实施过程以及临床实际应用,探讨单病例随机对照试验的设计和实施要点。
N-of- 1 trial design offers a methodologically sound approach to determining optimum treatment for an individual patient and solves some limitations of randomized controlled trials. This design could offer an efficient method of reaching a personal treatment regime tailored to suit individual needs and preferences. The paper introduces practical application, objects and the implementation process of N-of-1 trial, to explore its design points and implementation.
出处
《中国循证医学杂志》
CSCD
2017年第3期364-368,共5页
Chinese Journal of Evidence-based Medicine
基金
国家自然科学基金(编号:81273935
81303143)
关键词
单病例随机对照
设计
实施
应用
N-of-1 trial
Design
Implementation
Application
