基于数据挖掘的针灸治疗慢性疲劳综合征腧穴运用规律

Acupoint selection rules of acupuncture for chronic fatigue syndrome based on data mining technology

目的:分析针灸治疗慢性疲劳综合征(CFS)的腧穴运用规律。方法:系统检索和严格筛选后,建立针灸处方数据库,运用"针灸数据挖掘系统V1.0进行挖掘。结果:共纳入文献196篇,单腧穴使用频次和支持度前五位分别是足三里、肾俞、脾俞、肝俞、三阴交;"足三里+三阴交""三阴交+内关"分别在两穴配伍项集中支持度、置信度最高,"足三里+三阴交+百会"在三穴配伍项集中支持度和置信度均最高,"足三里+关元+肾俞+脾俞"在四穴配伍项集中支持度和置信度均最高。结论:针灸治疗CFS以辨病取穴为主,多选用足阳明、足太阳和足太阴腧穴,重视补益穴和背俞穴的使用,在配伍上多采用表里经配穴、交会经配穴和三部配穴,体现了重视先、后天调理的学术思想。

Objective： To analyze the acupoint selection rules of acupuncture for chronic fatigue syndorme （CFS） by using data mining technology. Methods： Combining subject headings and text words, retrieve Embase, Pubmed, Cochrane Library, CBM, CNKI, VIP, WanFang. Conducting strict screening according to inclusive/ exclusive criteria. Setting up the database of acupuncture prescription, input data. Using ＂acupuncture data mining system V1.0 （2009SR014647） ＂ to analyze the aeupoint regulation rules. Results： 196 articles, 218 acupuncture prescriptions were included. 43 acupoints were used for 1377 times in total. The top 5 frequently-used acupoints were ST36 （136/62.4%） , BL23 （92/42.2%） , BL20 （86/39.4%）, BL18 （84/38.5%）, SP6 （78/35.8%）. The most frequently-used 2 acupoints-combination was ST36→SP6 （29.4%） , 3 aeupoints-eomhination was ST36 ＋ SP6→DU20 （ 18.3% ） , and 4 acupoints-combination was ST36 ＋ RN4 ＋ BL23→ BL20 （12.8%）. Conclusion： Acupoint selection of CFS is given priority to disease differentiation. Points of Foot-Yangming Meridian, Foot-Taiyang Meridian and Foot-Taiyin Meridian are most frequently used. The use of tonifying points and Back-shn points is emphasized. ＂ST36 combines with acupoints on above meridian＂ is the fundamental acupoints combination. Cooperation of superficial-internal meridians, crossed meridians and local- nearby-distal acupoints show that we should tonify the root of body： spleen and kidney to treat CFS.