急性胆源性胰腺炎早期内镜逆行胰胆管造影及介入治疗的疗效分析

Endoscopic retrograde cholangiopancreatography and interventional therapy in the treatment of acute biliary pancreatitis

目的探讨急性胆源性胰腺炎早期内镜逆行胰胆管造影(ERCP)及介入治疗的临床疗效。方法将83例胆源性胰腺炎患者根据治疗方式的不同分为内镜治疗组42例和保守治疗组41例。内镜治疗组在保守治疗的基础上早期予以ERCP、EST或EPBD治疗,保守治疗组采用保守治疗,比较两组疗效。结果与保守治疗组相比,内镜治疗组患者在腹部疼痛症状缓解时间、血淀粉酶、肝功能及C反应蛋白的恢复时间、住院时间方面均有所减少,两组比较,差异具有统计学意义(P<0.05)。内镜治疗组并发症发生率低于保守治疗组,两组比较,差异具有统计学意义(P<0.05)。结论急性胆源性胰腺炎早期内镜治疗安全有效,具有对机体创伤小、恢复快、治愈率高及并发症低等特点,是安全有效的微创治疗方法,值得临床推广。

ObjectiveTo explore the clinical effect of endoscopic retrograde cholangiopancreatography and interventional therapy in the treatment of acute biliary pancreatitis. MethodsA total of 83 patients with biliary pancreatitis were divided into endoscopic treatment group（42 cases） and conservative treatment group（41 cases） according to the different treatment. Patients in the endoscopic treatment group were treated with ERCP、EST or EPBD on the basis of conservative treatment. Patients in the conservative treatment group received conservative treatment. The efficacy of the two groups were compared. ResultsCompared with the conservative treatment group, the abdominal pain relief time, blood amylase, liver function and C reaction protein recovery time, hospital stay time of endoscopic treatment group were reduced, the difference of was statistically significant （P〈0.05）. The complications rate of endoscopic treatment group was lower than that of the conservative treatment group, the difference was statistically significant （P〈0.05）. ConclusionsEarly endoscopic treatment for acute biliary pancreatitis is safe and effective, which has the characteristics of small wound, fast recovery, high cure rate and low complication.This technology is worthy of clinical promotion.