犀角地黄汤治疗小儿过敏性紫癜的临床疗效评价

Evaluation on the Clinical Effect of Rhinoceros Horn and Rehmannia Decoction in the Treatment of Children with Allergic Purpura

目的探讨犀角地黄汤治疗小儿过敏性紫癜的临床效果。方法选取我院2015年3月至2016年9月收治的114例过敏性紫癜患儿,随机分为研究组与对照组,各57例。研究组给予犀角地黄汤联合西咪替丁、潘生丁、钙剂及维生素C等西医治疗,对照组单纯给予常规西医综合治疗。分析比较两组患儿的治疗效果、相关症状体征消失时间及不良反应情况。结果研究组的总有效率明显高于对照组(P<0.05)。研究组的相关症状体征消失时间明显短于对照组(P<0.05)。两组的不良反应发生率比较差异无统计学意义(P>0.05)。结论采用犀角地黄汤治疗小儿过敏性紫癜能够明显提高治疗效果,促进症状缓解,安全可靠。

Objective To explore the clinical effect of rhinoceros horn and rehmannia decoction in the treatment of children with allergic purpura. Methods 114 cases of children with allergic purpura admitted to our hospital from March 2015 to September 2016 were selected and randomly divided into study group and control group, with 57 cases in each group. The control group was given conventional comprehensive western medical treatment with cimetidine, dipyridamole, calcium and vitamin C, while the study group was given rhinoceros horn and rehmannia decoction on this basis. The treatment effect, disappearance time of relative symptoms and signs, and adverse reactions were analyzed and compared between two groups. Results The total effective rate of study group was significantly higher than that of control group （P〈0.05）. The disappearance time of relative symptoms and signs of study group were significantly shorter than those of control group （P〈0.05）. No statistical difference was found in the incidence of adverse reactions between two groups （P〉0.05）. Conclusions Rhinoceros horn and rehrnannia decoction in the treatment of children with allergic purpura is safe and reliable, which can significantly improve treatment effect, and promote the remission of symptoms.