摘要
研究湖南产水菖蒲的化学成分。利用硅胶柱色谱和Sephadex LH-20柱色谱技术从水菖蒲95%乙醇浸提物中分离得到1个倍半萜类成分,结合波谱和X射线单晶衍射数据,鉴定该化合物为1R,5R,7S-guaiane-4R,10R-diol-6-one,是1个新的愈创木烷型倍半萜。
A new quaiane-tgpe sesquiterpene was isolated from the 95% ethanol extract of the rhizomes of Acorus calamus by silica gel and sephadex LH-20 column chromatographic methods. Structure and absolute configuration of the sesquiterpene were elucidated by spectroscopic data and X-ray crystallographic analysis,and named as 1R,5R,7S-guaiane-4R,10R-diol-6-one.
作者
李娟
李兆星
赵小芳
徐博
李林
张兰
李顺祥
LI Juan LI Zhao-xing ZHAO Xiao-fang XU Bo LI Lin ZHANG Lan LI Shun-xiang(Hunan Province Engineering Research Center of Bioactive Substance Discovery of Traditional Chinese Medicime , Hunan University of Chinese Medicine, Changsha 410208, China College of Pharmacy, Southwest Liniversity, Chongqing 400716, China Key Laboratory of Neurodegenerative Diseases of Ministry of Education, Capital Medical University, Be~jing 100053, China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2017年第4期708-711,共4页
China Journal of Chinese Materia Medica
基金
湖南省教育厅项目(15C0114)
神经变性病教育部重点实验室(首都医科大学)2016年开放研究课题
湖南"中药学"重点学科项目(湘教通[2011]76号)
