DUR与DUE方法在社区获得性肺炎患者用药情况评价中的应用效果

Application effect of DUR and DUE in the evaluation of drug use in patients with community acquired pneumonia

目的评估药物利用评价(DUR)与药物利用评估(DUE)方法在社区获得性肺炎患者用药情况评价中的应用效果。方法通过DUR以及DUE的方法,对广州市天河区人民医院2015年1月~2016年8月呼吸科治疗出院的107例社区获得性肺炎患者的相关用药情况进行综合分析。结果患者治疗采用的抗菌药共21种,其中5种药物的DUI>1,分别为注射用头孢呋辛钠、头孢他啶、阿莫西林分散片、伊曲康唑胶囊、头孢吡肟。评估结果为处方量过大,存在用药不合理的现象。对入院患者进行治疗的过程中,有7例出现药物不良反应,经过治疗后96.3%的患者出现明显好转。另有4例患者放弃住院治疗。结论联合使用DUR和DUE法能够更加全面地对基层医院的抗菌药使用进行评价,及时发现不合理用药现象,促进药品资源的管理,促使医院建立和完善用药体系。

Objective To evaluate the application effect of DUR and DUE in the evaluation of drug use in patients with community acquired pneumonia.Methods 107 patients with community acquired pneumonia treated in Department of Respiration of People′s Hospital of Tianhe District in Guangzhou City from January 2015 to August 2016 were comprehensively analyzed by DUR and DUE.Results A total of 21 antimicrobial agents were used in the treatment of patients,and drugs DUI of 5 cases were more than 1,which were Cefuroxime Sodium,Ceftazidime,Amoxicillin Dispersible Tablets,Itraconazole Capsules and Cefepime.The evaluation results showed that prescription were too large and drug used were irrational.7 patients had adverse drug reactions in the process of hospitalization,96.3% of the patients showed obvious improvement after treatment.Another 4 patients abandoned hospitalization.Conclusion The combined used of DUR and DUE can evaluate the use of antimicrobial agents in primary hospitals more comprehensively,discover unreasonable drug use,promote the management of drug resources,and promote the establishment and perfection of hospital drug system.