腹泻患儿标本病原菌的监测及药敏情况分析

Monitoring and drug susceptibility analysis of pathogenic bacteria samples of children with diarrhea

目的:分析腹泻患儿标本病原菌的监测及药敏情况,为临床患儿腹泻的治疗提供参考。方法:选取在2013年1月至2016年1月期间收治的200份腹泻患儿的粪便进行分离培养,具体分析病原菌的检出率与主要病原菌的药敏情况。结果:200份粪便经培养,共检出病原菌112株,检出率为56.00%(112/200),其中主要致病菌为沙门氏菌(37.50%)、志贺氏菌(12.50%)、铜绿假单胞菌(28.57%)、大肠埃希菌(10.71%);其中沙门氏菌、志贺氏菌与大肠埃希菌对于临床上常用的抗生素具有较高的耐药性,而铜绿假单胞菌的耐药性情况较好。结论:临床上应及时监测腹泻患儿病原菌与药敏情况,应加强抗生素的滥用管理工作,提高临床用药的科学性与严谨性,为降低致病菌的耐药性具有重要的临床意义。

Objective：To conduct the monitoring and drug susceptibility analysis of pathogenic bacteria samples of children with diarrhea, and to provide a reference for clinical treatment of children with diarrhea. Methods ：200 cases of dung in children with diarrhea were separated and cultured, with relevance ratio of pathogenic bacteria and the drug susceptibility of the main pathogen analyzed. Results： In 200 samples cultured, pathogenic bacteria was checked out in 112 strains, and the detection rate was 56.0（3 % （112/200）. The main pathogenic bacteria involved sal- monella （37.50 % ） , shigalla bacteria （ 12.50 % ） , pseudomonas aeruginosa （28.57 % ） , and e. coli （ 10.71% ）. Salmonella, shigalla bacte- ria and e. coli had high drug resistance for commonly - used antibiotics in clinic. And pseudomonas aeruginosa in resistance was better. Conclusion ： Timely monitoring of the pathogens and drug susceptibility of children with diarrhea in clinic, along with strengthened management of antibiotics abuse and with more precise and scientific administration, has important clinical significance in reducing the drug resistance of pathogenic bacteria.