米非司酮辅助利凡诺用于中期妊娠引产的疗效

The effect of rivanol combined with mifepristone on the induction of labor in mid-term pregnancy

目的:探讨米非司酮辅助利凡诺用于中期妊娠引产的疗效。方法:选取118例中期妊娠要求引产的孕妇随机分为观察组和对照组,各59例,分别给予米非司酮辅助利凡诺和单纯利凡诺引产,比较两组的孕妇引产疗效,注药至宫缩时间、宫缩至胎盘排出时间、子宫出血量及并发症等指标。结果:观察组孕妇的引产疗效总有效率高于对照组(P<0.05);注药至宫缩时间、宫缩至胎盘排出时间较对照组孕妇缩短(P<0.05);子宫出血量低于对照组(P<0.05);观察组孕妇的软产道裂伤和胎盘胎膜残留发生率较对照组低(P<0.05)。结论:米非司酮辅助利凡诺用于中期妊娠引产可显著提高引产的成功率,缩短引产的时间,减少子宫出血量,降低并发症的发生率,值得在临床上推广。

Objective ：To investigate the effect of rivanol combined with mifepristone on the induction of labor in mid - term pregnancy. Methods： 118 pregnant women who were asked to in- duce labor during the second trimester were randomly divided into the experimental group and the control group. The experlmental group was injected by rivanol combined with mifepristone while the control group was injected by mifepristone only, the efficacy of induction of labor, the time from injection to contraction, the time from contraction to placental discharge, the amount of uter- ine bleeding and the complications of the two groups compared. Results：The total effective rate of induction of labor in the experimental group was higher than that in control group（ P 〈 0.05） ; the time from injection to contraction, the time from contraction to placental discharge in the experimental group were shorter than those in the control group（ P 〈 0.05） ; the amount of uterine bleeding in the experimental group was less than that in the control group（ P 〈 0.05 ） ; the rates of soft birth canal laceration and fetal membrane residuals were lower than those of the control group （ P 〈 0.05）. Conclusion： Rivanol combined with mifepristone is beneficial to the induction of labor in mid - term pregnancy. It can significantly improve the success rate of induction of labor, shorten the induction time, reduce the amount of uterine bleeding and reduce the incidence of complications, which is worth further promotion in clinical practice.