降钙素原、C反应蛋白、血小板及嗜酸性粒细胞对脓毒症患者预后的影响

Effect of procalcitonin,C-reactive protein,platelet and eosinophil on the prognosis of patients with sepsis

目的：探讨血小板（PLT）及嗜酸性粒细胞和降钙素原（PCT）、C反应蛋白（CRP）水平在脓毒症患者预后判断中的意义。方法：选取急诊收入的脓毒症患者104例,根据预后分为存活组及病死组,分别检测2组患者PLT及嗜酸性粒细胞和PCT、CRP水平。结果：2组患者嗜酸性粒细胞差异无统计学意义（P〉0.05）,而PLT、PCT及CRP差异均有统计学意义（P〈0.05~P〈0.01）。PCT、CRP进入logistic回归模型,而PLT未能进入。结论：PLT是影响预后的影响因素,PCT、CRP水平是影响脓毒症的独立危险因素,嗜酸性粒细胞对脓毒症患者的预后无明显影响。

Objective： To explore the significance of platelet（ PLT）,eosinophil,procalcitonin（ PCT） and C-reactive protein（ CRP） in judging the prognosis of patients with sepsis. Methods： One hundred patients with sepsis from department of emergency were divided into the survival group and death group according to the prognosis. The levels of PLT,eosinophil,PCT and CRP in two groups were observed. Results： The difference of the level of eosinophil in different prognosis patients was not statistically significnat（ P〉0. 05）,but the differences of the levels of PLT,PCT and CRP in different prognosis patients were statistically significnat（ P〈0. 05 to P〈0. 01）.The PCT and CRP could be analyzed using logistic regression model,while PLT could not. Conclusions： PLT is an independent influence factor for prognosis,PCT and CRP are the risk factors for sepsis,and eosinophil is not associated with the prognosis of patients with sepsis.