HIV感染者/AIDS患者进行抗病毒治疗生命质量研究

Study on life quality of HIV/AIDS patient antiviral therapy

[目的]了解HIV感染者/AIDS患者进行抗病毒治疗后的生命质量及影响因素,为建立适宜我国艾滋病抗病毒治疗管理方式提供依据。[方法]采取随机抽样方法,使用《HIV感染者/AIDS患者生命质量测定量表(QLICD-HIV 2.0)》进行调查,使用SPSS统计软件分析数据。[结果]收集到合格问卷调查表405份,各领域得分分别为:生理功能(65.16±14.28)分、心理功能(59.75±16.19)分、社会功能(61.71±17.68)分、特异功能(65.58±20.28)分。从高到低排列,特异模块>生理功能>社会功能>心理功能,领域得分经方差分析,差异有统计学意义(P<0.05)。单因素分析显示:性别、不同年龄、婚姻状况、感染途径及WHO临床分期因素影响HIV感染者/AIDS患者生命质量的不同领域;不同CD4分组及病毒载量分组在4个领域得分差异均无统计学意义(P>0.05)。[结论]HIV感染者/AIDS患者接受抗病毒治疗后,相关机会性感染得到及时治疗,免疫功能得到提升,生存时间延长。但要提高患者整体生命质量,应把更多的心理关怀、社会支持融入到抗病毒治疗管理工作中。

Objective To understand life quality and its influencing factors after HIV/AIDS patients accept antiviral therapy so as to provide evidence for establishing suitable HIV/AIDS antiviral therapy management mode. Methods It used random sampling method and investigated by＂HIV/AIDS patients life quality determination scale（ QLICD-HIV 2. 0）,analyzed the data by SPSS statistical software. Results Collected qualified questionnaires 405. The score of each field was that physiological function（ 65. 16 ＋ 14. 28）, psychological function（ 59. 75 ＋16. 19）,social function（ 61. 71 ＋ 17. 68）,the specific function（ 65. 58 ＋ 20. 28）. From high to low,specific module,physiological function,social function and psychological function. There was statistically significant through variance analysis on the field（ P〈0. 05）. Single factor analysis showed that gender,age,marital status,infection route and WHO clinical stages factors influenced different field of HIV/AIDS patients＇ life quality. There was not statistically significant in different CD4 group and viral load groups which were in 4 fields（ P〉0. 05）. Conclusions After HIV/AIDS patients receiving antiretroviral therapy,the relevant opportunistic infections received timely treatment,immune function was improved,survival time was extension. But it need to improve patients＇ overall life quality,and integrate much psychological care and social support into antiviral therapy management.