摘要
为研究艾叶烟熏对正常呼吸道的组织学影响,将54只健康SPF昆明系小鼠分为对照组、2 g艾叶/m^3组和4 g艾叶/m^3组,艾叶烟熏疗程,分为艾叶烟熏1次、1周和2周。结果可见:艾叶烟熏能造成小鼠肺脏和气管的水肿;2 g艾叶/m^3组艾叶烟熏后气管黏膜上皮细胞脱落数量出现先升后低的变化,艾叶烟熏2周试验组气管黏膜上皮细胞脱落数低于对照组但并无显著差异;艾叶烟熏2周试验组鼻黏膜上皮细胞间杯状细胞数量与对照组相比较具有显著性增加。结果表明,艾叶烟熏能造成小鼠肺脏和气管的水肿,但没有进一步的组织损伤。适宜浓度的艾叶烟熏能加强呼吸道黏膜的完整性,并能增加杯状细胞的数量,增加呼吸道黏液分泌。
To study the histological effect in normal respiratory tract by different Moxa-smog treatment, 54 healthy SPF KM mice were divided into control group, 2 g Argyi/m^3 group, and 4 g Argyi/m^3 group. Mice in each group were exposed in Moxa-smog twice a day and continue 2 weeks. Results ： After Moxa-smog treatment, the number of goblet cells in nasal mucosa increased significantly. However. the number of mast cells in nasal mucosa did not changed significantly; the lung and trachea had slight edema; In 2 g Argyi/m^3 group, the amount of tracheal exfoliated epithelium increased and then decrease. Our results show that the suitable concentration of Moxa-smog can enhance the integrity of respiratory epithelium as well as the mucus secretion, and increase the number of goblet cells.
出处
《中国兽医杂志》
CAS
北大核心
2017年第1期109-111,F0003,共4页
Chinese Journal of Veterinary Medicine
基金
中央高校基本科研业务费专项资金(2015DY004)
中国农业大学动物医院临床基金
关键词
艾叶烟熏
小鼠
呼吸道黏膜上皮
杯状细胞
Moxa-smog
respiratory symptom
goblet cell
respiratory epithelium
