长骨骨不连的研究进展

Research progress of long bone nonunion

长骨骨不连是骨科医生常需面对的一个棘手问题。目前Weber-Cech分类法仍是临床上最常用的分类标准,骨不连的诊断仍以美国FDA的骨不连标准最为多用。对不同类型的骨不连,治疗方法也不尽相同。近些年国内外对骨不连做了更深入的研究,在传统的髓内钉、钢板螺钉、外固定架等手术治疗基础上提出了一些新的理念和方法,如干细胞移植及基因治疗等。本文总结目前已发表的文献,以期为临床医生更进一步研究骨不连以及临床上选择正确合理的治疗方法提供参考。

Long bones nonunion is a difficult problem which clinicians need to face currently. The most commonly used classification criteria by clinicians is Weber-Cech classification. The most commonly used diagnosis standard of bone nonunion is established by US Food and Drug Administration. Different types of bone nonunion need different treatment methods. In recent years much has been done on long bone nonunion both at home and abroad,some new ideas and methods were raised on the basis of the traditional intramedullary nail,plate and screw and external fixation operation therapy,including stem cell transplantation and gene therapy. Latest literature has been summarized so as to provide reference for clinicians to make further study for bone nonunion and to choose correct and reasonable treatment for patients.