摘要
目的总结布鲁菌病性睾丸炎的临床特征及治疗预后情况,为临床诊治提供参考。方法回顾性选取2012—2016年期间明确诊断为布鲁菌病的男性患者73例中并发睾丸炎者12例(16.4%),入院时完善血液学检测及睾丸B超检查,住院期间给予有效的抗菌药物治疗并定期随访复查,治疗结束后复查血液学各项指标。结果 12例布鲁菌病性睾丸炎患者的平均年龄(37.58±10.40)岁,就诊时平均病程为(8.83±6.22)d。抗菌药物治疗后患者的缓解期平均为(15.50±5.92)d。发热、睾丸肿痛是常见的症状,同时合并骨关节系统并发症和肝损害常见。患者丙氨酸转氨酶、红细胞沉降率、C反应蛋白入院时多高于正常水平,治疗结束后均明显下降。结论在布鲁菌病的高发地区,对于睾丸炎患者应考虑布鲁菌感染的可能。布鲁菌病性睾丸炎除了具有睾丸局部红、肿、热、痛的炎症表现外,可伴有明显的全身症状,须给予三药联合的抗菌药物组合方案,小剂量糖皮质激素及局部物理治疗可起到很好的效果,推荐疗程12周。
Objective To summarize the clinical characteristics and prognosis of Brucella orchitis, and provide reference for its clinical diagnosis and treatment. Methods Among 73 brucellosis patients in the Yumin county hospital during 2012-2016, 12 patients(16.4%) complicated with Brucella orchitis. Blood test and testicular ultrasound examination were applied to these cases on admission, effective antibacteria treatment was used during hospitalization, and blood biochemical indexes were reviewed at the end of therapy. Results The mean age of 12 Brucella orchitis patients was(37.58±10.40) years old, mean course of disease before admission was(8.83±6.22) days and the average time of paracmasia was(15.50±5.92) days after the antibacterial treatment. Fever and testicular swelling pain were the common symptoms. Most of the patients had osteoarthritis system involvement and liver damage. Alanine transaminase, erythrocyte sedimentation rate and C-reactive protein were beyond the normal range on admission, but decreased significantly after treatment. Conclusions In epidemic area of brucellosis, Brucella infections should be considered in patients with testicular inflammation. In addition to the manifestation of orchitis inflammation, such as: red, swollen, hot and pain, Brucella orchitis could accompany by obvious systemic symptoms. Combination of three antibacterial drugs is needed, small doses of corticosteroids and local physical therapy will have very good effects, and the recommended treat duration is 12 weeks.
出处
《传染病信息》
2017年第1期48-50,共3页
Infectious Disease Information
基金
新疆维吾尔自治区重点研发计划项目(2016B03047-1)