摘要
Insulin signaling is vital for the development and growth of mammals,which also plays a prominent role in the regulation of metabolism,stress response,reproduction,and behaviors.Therefore,insulin signaling is under tight regulation at the levels of insulin biosynthesis,secretion,and post-secretion action（Melloul et al.,2002;Na€ssel et al.,2013）.
Insulin signaling is vital for the development and growth of mammals,which also plays a prominent role in the regulation of metabolism,stress response,reproduction,and behaviors.Therefore,insulin signaling is under tight regulation at the levels of insulin biosynthesis,secretion,and post-secretion action（Melloul et al.,2002;Na€ssel et al.,2013）.
基金
funded by the Thousand Young Talents Plan,the National Natural Science Foundation of China(No.31522026)
the Fundamental Research Funds for the Central Universities(No.2016QN81010)
