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小型猪耳蜗多平面重组技术的临床应用价值

The Clinical Application Value of Cochlear Multi-planar Reconstruction of the Miniature Pig
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摘要 目的探索耳蜗多平面重组技术的要点及临床应用价值。方法3只正常的小型猪颞骨行Micro-CT扫描,所得的图片导入Mimics软件中并行内耳的三维重建。通过Mimics软件的在线重切片功能获得连续的耳蜗横截面图像。利用软件自带的测量工具包测量前庭阶及鼓阶的相关参数。结果小型猪颞骨图像重组后能够清晰的显示耳蜗内的精细结构,同时获得了小型猪沿耳蜗全长分布的鼓阶及前庭阶参数(横截面积、宽度及高度)。结论耳蜗MPR(multi-planar reconstruction)技术提供耳蜗全长鼓阶及前庭阶的结构和大小,可以为临床人工耳蜗植入术,特别是疑难复杂的人工耳蜗植入术提供更全面的资料,指导术者选择合适的植入电极,减少植入损伤。 Objective To explore the technology and the clinical application value of the cochlear multi-planar reconstruction (MPR) technique. Methods The temporal bones of three miniature pigs with normal hearing were scanned by micro-CT. All images were input into Mimics software, thus reconstructing the 3D structure of the inner ear, obtaining the serial cross-sectional images through the "online reslice" function of the software, and measuring the detailed dimensions of the vestibular and tympanic scalae. Results The reslicing images displayed the fine structures within the cochlea clearly; meanwhile, we gained the detailed dimensions(area,width and height) of the vestibular and tympanic scalae along the cochlear length of the miniature pig. Conclusion The application of MPR technique may be a new approach to providing more detailed information of the patients to guide the surgeries choosing the more suitable implanted electrodes for reducing the implantation injury.
出处 《中国听力语言康复科学杂志》 2017年第2期92-96,共5页 Chinese Scientific Journal of Hearing and Speech Rehabilitation
基金 国家973计划重大科学研究计划干细胞项目(2012CB967900) 国家973计划重大科学问题导向项目(2011CBA01000) 国家自然科学基金青年项目(81400472)
关键词 小型猪 多平面重组 体层摄影术 X线计算机 植入损伤 lMiniature pig Multi-planar reconstruction Tomography X-ray computed Implantation injury
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