精准外科在结直肠癌根治术中的临床实践及意义

Clinical practice and significance of the precision surgery in radical resection of colorectal cancer

随着基因组学、生物分析技术、影像诊断和外科技术的发展,肿瘤患者术前精准临床分期判断及分子生物学信息的获得使得个体化的精准医疗成为可能,结直肠肿瘤的外科治疗开始逐步迈向"精准医学"时代。肿瘤的精准外科治疗是在标准根治术的基础上,利用现代影像学和分子病理诊断技术对肿瘤类型及分期进行精确全面的术前诊断,细致周全的术前准备,精细准确的手术操作和术后康复计划,最大限度减少手术创伤及保留脏器功能,快速促进患者康复。本文我们将探讨精准外科在结直肠癌根治术中的临床实践及意义,旨在进一步推广精准外科治疗理念,推进我国胃肠肿瘤防治事业的进步。

With the development of cancer genomics, emergency of biological technology, imaging diagnosis and surgical techniques, cancer patients with preoperative accurate diagnosis of clinical staging and molecular biology information have made personalized treatment possible. The surgical treatment of rectal tumor is gradually moving towards the era of ″precision medicine″. Based on the standard radical surgery, the precise cancer surgery included accurate diagnosis of tumor types and stages by modern imaging and molecular pathological techniques, detailed therapeutic strategy before surgery, minimally surgical trauma and maximally preserving organ function by the latest surgical techniques and quickly promoting the rehabilitation of patients. Here, we discussed the significance and clinical practice of precision medicine in colorectal cancer radical surgery that would promote the prevention and control of gastrointestinal cancer in our country.