针刺配合天麻素穴位注射治疗脑梗死临床疗效及对血液流变学指标的影响研究

Clinical Therapeutic Effects of Acupuncture and Gastrodin Injection on Cerebral Infarction and the Impacts on Hemorheological Indicators

目的评价针刺配合天麻素穴位注射方式在脑梗死患者中的治疗效果,同时探讨对患者机体血液流变学指标的影响变化。方法将136例脑梗死患者按照随机数字表法分为对照组与治疗组,每组68例。对照组患者采用舒血宁注射液静脉滴注,治疗组患者采用中医针刺配合天麻素注射液穴位治疗。7 d为一个疗程,每一疗程间隔3 d,连续治疗3个周期后。观察两组患者治疗后临床总有效率,中医证候积分及神经功能缺损评分,统计分析两组患者治疗前后血液流变学指标的变化。结果 (1)治疗后治疗组与对照组临床总有效率分别为94.12%、75.00%,两组比较差异有统计学意义(P<0.05);(2)治疗后两组中医证候积分、神经功能缺损评分与治疗前比较均显著降低,差异有统计学意义(P<0.05),且治疗组两个指标降低程度优于对照组,差异有统计学意义(P<0.05);(3)两组治疗后血液流变学指标与治疗前比较均降低,差异有统计学意义(P<0.05),且治疗组各项指标降低程度更加优于对照组,两组比较差异有统计学意义(P<0.05)。结论针刺配合天麻素注射液穴位注射可以明显提高患者的临床治疗效果,有效改善患者的血液流变学各项指标,对中医证候积分、神经功能缺损程度具有积极的治疗效果,促进患者神经功能的恢复,值得临床推广应用。

Objective To evaluate the therapeutic results of acupuncture and acupoint injection with gastrodin in the patients of cerebral infarction and explore the impacts on hemorheological indicators.Methods One hundred and thirty-six patients of cerebral infarction were divided into a control group and a treatment group according to random number table,68 cases in each one. In the control group,the intravenous injection with shuxuening was used. In the treatment group,acupuncture was used and combined with acupoint injection with gastrodin. The treatment for 7 days was as one session. There were 3 days at the interval among sessions. Three sessions were given continuously. The total effective rate,TCM syndrome score and neural function defect score were observed after treatment. The changes in hemorheological indicators were analyzed statistically before and after treatment. Results 1. The total effective rate was 94. 12% in the treatment group and was 75. 00% in the control group after treatment,indicating the significant difference（P〈0. 05）. 2. TCM syndrome score and neural function defect score were reduced significantly as compared with those before treatment,indicating the significant difference（P〈0. 05）. The two indicators in the treatment group were reduced more apparently as compared with that in the control group,indicating the significant difference（P〈0. 05）. 3. After treatment,the hemorheological indicators were all reduced as compared with those before treatment in the two groups,indicating the significant difference（P〈0. 05）. The reducing degree in the treatment group was better than that in the control group,indicating the significant difference（P〈0. 05）. Conclusion Acupuncture and acupoint injection with gastrodin apparently improve the clinical therapeutic effects and the hemorheological indicators and reduce the scores of TCM syndrome and neural function defect actively.This therapy promotes the recovery of neural function and deserves to be promoted in clinical application.