神经内科医院感染病原菌感染特点与多药耐药菌感染研究

Characteristics of nosocomial infections caused by pathogens and multidrug-resistant organisms infections in neurology department

目的研究神经内科医院感染病原菌感染部位与多药耐药菌感染情况,为神经内科医院感染的预防控制提供参考依据。方法选取神经内科2011年1月-12月85例感染患者为A组,2012年1月-12月88例感染患者为B组,2013年1月-12月89例感染患者为C组,2014年1月-12月91例感染患者为D组,2015年1月-12月90例感染患者为E组,然后统计及比较五组患者的标本分布、病原菌感染部位及多药耐药菌感染情况。结果五组患者痰标本所占比例分别为52.94%、51.14%、51.69%、51.68%及52.22%,均高于其他标本(P<0.05),肺部感染所占比例分别为53.41%、55.68%、55.06%、54.95%及56.67%,均明显高于其他感染部位(P<0.05),D组及E组多药耐药菌比例均高于A组、B组及C组,C组则高于A组及B组(P<0.05)。结论 2011-2015年神经内科医院感染病原菌感染部位均以肺部为主,且多药耐药菌所占比例呈现升高趋势,应给予充分的重视及干预。

OBJECTIVE To study the sites of nosocomial infections caused by pathogens in neurology department and analyze the prevalence of multidrug-resistant organisms （MDROs） infections so as to provide guidance for prevention and control of the nosocomial infections in neurology department. METHODS Totally 85 patients with infections who were treated in neurology department from Jan 2011 to Dec 2011 were chosen as the group A, 88 patients with infections who were treated from Jan 2012 to Dec 2012 were set as the group B, and 89 patients with infections who were treated from Jan 2013 to Dec 2013 were assigned as the group C, 91 patients with infections who were treated from Jan 2014 to Dee 2014 were chosen as the group D, and 90 patients with infections who were treated from Jan 2015 to Dec 2015 were set as the group E. The distribution of specimens, infection sites, and prevalence of MDROs infections were statistically analyzed and compared among the five groups of patients. RESULTS The proportions of sputum specimens of the five groups of patients were respectively 52. 94%, 51. 14%, 51.69%, 51.68%, and 52.22%, higher than those of other specimens （P%0.05）. The proportions of the patients with pulmonary infections were 53.41%, 55.68%, 55. 06%, 54.95%, and 56.67%, significantly higher than those of the patients with other sites of infections （P〈0.05）. The proportions of MDROs were higher in the group D and E than in the group A, B, and C, which, however, were higher in the group C than in the group A and B. CONCLUSION The lung is the major infection site of the patients with nosocomial infections in the neurolo- gy department from 2011 to 2015, the proportion of MDROs shows an upward trend, and it is necessary to pay high attention to and take interventions.